Hypersensitivity following Retreatment with Carboplatin a Decade after Completion of Primary Platinum-Based Chemotherapy
نویسندگان
چکیده
The relatively rapid development of a platinum-associated hypersensitivity reaction in an ovarian cancer patient receiving second-line chemotherapy more than a decade following her last course of primary platinum-based chemotherapy demonstrates that the prolonged persistence of immune cells recognizing platinum after sensitization has been established.
منابع مشابه
Retreatment of recurrent invasive thymoma with platinum, doxorubicin, and cyclophosphamide.
Invasive thymoma recently has been shown to be sensitive to combination chemotherapy and in some cases to be relatively indolent. Two cases of extensive thymoma which responded to primary treatment with a combination of a platinum compound (carboplatin or cisplatin), doxorubicin (Adriamycin), and cyclophosphamide (or PAC) are described. Tumor progression occurred 14 (case 1) and 60 months (case...
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